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Fig. 5 | Molecular Cancer

Fig. 5

From: RETRACTED ARTICLE: LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis

Fig. 5

PVT1 made an effort on autophagy via regulation of ULK1. a Western blot analysis of LC3b in Capan-2 and MIA PaCa-2 cells with or without up-regulation of PVT1. It was observed that the level of LC3b II was enhanced after increase of PVT1 expression; b LC3b II expression was decreased after down-regulation of PVT1; c Western blot analysis of LC3b in PVT1 stable-expressed Capan-2 and MIA PaCa-2 cells with or without depletion of ULK1. Suppression of LC3b II expression was detected after depletion of ULK1; d LC3b II expression was rescued after restoration of ULK1 in PVT1-knowndown SW1990 and HPAF-II cells

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Molecular Cancer

ISSN: 1476-4598