Fig. 5
From: MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling
Anti-apoptotic proteins Bcl-xL and/or Survivin are downregulated in MASTL knockdown cells. (a & b) Bcl-xL and/or Survivin were downregulated with MASTL knockdown in both HCT116 and SW620 cells compared to control cells. For graphs, data represent mean ± SD;**, P < 0.001; ***, P < 0.0001 versus control. (c & d) β-catenin expression, activity and localization and c-Myc expression were altered in MASTL inhibited cells. (e) p-GSK-3β expression is altered with modulation of MASTL expression