Fig. 7
From: Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer
PDHX inversely correlates with miR-27b in human tissues and is associated with improved prognosis and survival. Correlation plots of PDHX and miR-27b TCGA expression data grouped according to luminal A (a) and ER+ (b) varieties. b TCGA data indicating the association between PDHX expression and breast cancer recurrence. Survival curves of breast cancer patients according to PDHX expression status, shown as DFS (c) and OS (d). Median survival time is shown in brackets. Sorlie Breast Cancer Database statistics showing the association of PDHX with recurrence (e) and survival status in breast cancer patients (f). g Schematic illustrating the miR-27b/PDHX regulatory axis and its functions in regulating cancer cell energy metabolism