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Fig. 2 | Molecular Cancer

Fig. 2

From: RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer

Fig. 2

Upregulation of RASAL2 is associated with poor prognosis and metastasis of CRC. a Representative IHC images showing positive (H-score > 100) and negative (H-score ≤ 100) RASAL2 expression in CRC. b The distribution of RASAL2 histoscore in RAS wild-type and mutant CRC samples. c RASAL2 overexpression had significantly shorter disease-free survival and overall survival in a cohort of 208 CRC patients. d-e Copy number gain (d) and upregulated mRNA levels (e) of RASAL2 showed aggressive disease-free survival and overall survival in TCGA CRC cohort

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