Fig. 7
From: The long non-coding RNA CYTOR drives colorectal cancer progression by interacting with NCL and Sam68
NCL and Sam68 acted as oncogenes and promoted CRC progression. a Higher expression of NCL in colorectal cancer than paired matched normal tissue samples from the GDS2947 and TCGA databases. b Higher expression of Sam68 in colorectal cancer than paired matched normal tissue samples from the GDS2947 and TCGA databases. c Positive correlation between CYTOR, NCL and Sam68 expression in the GSE38832 database. d Kaplan-Meier plots of overall survival versus NCL in CRC samples from our tissue bank, higher NCL expression with poorer survival. e Kaplan-Meier plots of overall survival versus Sam68 in CRC samples from our tissue bank, higher Sam68 expression with poorer survival. f Immunoblotting for detection of NCL and Sam68 in SW620 cells knocked down by siRNAs of NCL and Sam68. g Decrease of the proliferation ability for NCL knockdown (siNCL) and Sam68 knockdown (siSam68) SW620 cells compared with control (siNC) by CCK-8. h Decrease of migration/invasive potentials for NCL knockdown (siNCL) and Sam68 knockdown (siSam68) SW620 cells compared with control (siNC) by Transwell assay. i Expression of E-cadherin and Vimentin in NCL and Sam68 knockdown SW620 cells by immunoblotting