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Fig. 2 | Molecular Cancer

Fig. 2

From: Genome-scale CRISPR-Cas9 knockout screening in gastrointestinal stromal tumor with Imatinib resistance

Fig. 2

GeCKO screening in GIST-T1 cells reveals genes and miRNAs whose loss confers imatinib resistance. a & b Number of genes/miRNA with 0, 1, 2, 3 or 4 significantly enriched hGeCKOa (a) and hGeCKOb (b) sgRNAs targeting that genes/miRNA. Genes/miRNAs were selected by total reads of sgRNA and sgRNA diversity, as shown in black boxes. c Total reads of sgRNA for selected genes/miRNAs. d Gene ontology of candidate genes

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