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Fig. 1 | Molecular Cancer

Fig. 1

From: LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression

Fig. 1

The identification of a ceRNA network for mesenchymal OvCa. a The ceRNA network in mesenchymal OvCa. Rounded rectangles, ellipses and hexagons denote lncRNAs, EMT genes and miRNAs, respectively. Up-regulated lncRNAs, EMT genes and miRNAs are shown in red and down-regulated lncRNAs, EMT genes and miRNAs are shown in green. b ZEB1 was significantly up-regulated in mesenchymal OvCa compared with epithelial OvCa in the TCGA data set. c Positive correlation between PTAR and ZEB1 expression in the TCGA data set. d The lncRNA PTAR was significantly up-regulated in mesenchymal OvCa compared with epithelial OvCa in the TCGA data set. e Nagative correlation between miR-101 and ZEB1 expression in the TCGA data set. f Nagetive correlation between PTAR and miR-101 expression in the TCGA data set. g miR-101 was significantly down-regulated in mesenchymal OvCa compared with epithelial OvCa in the TCGA data set

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Molecular Cancer

ISSN: 1476-4598