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Fig. 7 | Molecular Cancer

Fig. 7

From: LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression

Fig. 7

Overexpression of miR-101 attenuated TGF-β1-induced metastasis in OvCa cell lines. a, b Wound healing assays performed in SKOV3 and A2780 cells, respectively. Images were captured at 0, 24, and 48 h. n = 4, *P < 0.05 vs. Ctrl, #P < 0.05 vs. TGF-β1. c, d The migration ability of SKOV3 and A2780 cells was determined using transwell assays. n = 4, **P < 0.01. e The expression levels of epithelial and mesenchymal markers were detected by western blot in SKOV3 cells. n = 5, *P < 0.05 vs. Ctrl, #P < 0.05 vs. TGF-β1. f Up-regulation of lncRNA PTAR enhanced ZEB1 expression by competitively binding miR-101, which promoted OvCa cell EMT and invasion

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