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Fig. 1 | Molecular Cancer

Fig. 1

From: SPAG5 interacts with CEP55 and exerts oncogenic activities via PI3K/AKT pathway in hepatocellular carcinoma

Fig. 1

SPAG5 expression is increased in HCC and associated with poor outcomes. a The mRNA expression of SPAG5 in 27 pairs of HCC (T) and nontumorous (N) tissues was determined by qRT-PCR. b Studies from Oncomine datasets presented the increase of SPAG5 mRNA in HCC samples. c The protein expression of SPAG5 in HCC cases were examined by western blot. The representative images and the statistical analysis were indicated. d The expression of SPAG5 in nontumorous, HCC and metastatic tissues was detected by IHC. The representative images and the IHC scores were shown. e The clinical significance of SPAG5 expression in overall and disease-free survivals was evaluated in SYSUCC cohort by Kaplan-Meier survival analyses. f. The prognostic value of SPAG5 was confirmed in TCGA cohort. All **P < 0.01, ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598