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Fig. 1 | Molecular Cancer

Fig. 1

From: Exosomal double-stranded DNA as a biomarker for the diagnosis and preoperative assessment of pheochromocytoma and paraganglioma

Fig. 1

Exosomes contain double-stranded genomic DNA. A The characteristics of exosomes were determined by electron microscopy. B Exosomes were also characterized by the expression of exosome-specific CD9, CD63, and TSG101 using western blotting. C The presence and concentration of exosomes in the sera of PCC and PGL patients was detected using NanoDrop™ 2000 and Transmission electron microscopy (n = 15). D To exclude genomic DNA and RNA contamination after exosomal DNA extraction, the DNA eluted from PC12 cells (Exo-DNA I), mutated xenografts (Exo-DNA II), PCC or PGL tumors (Exo-DNA III), or the corresponding exosomes was treated with DNase I and RNase A

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