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Fig. 2 | Molecular Cancer

Fig. 2

From: Exosomal double-stranded DNA as a biomarker for the diagnosis and preoperative assessment of pheochromocytoma and paraganglioma

Fig. 2

Exosomes contain mutated RET, HIF2A, VHL, and SDHB DNA. A iPLEX® mutation analysis of genomic DNA from PC12 and corresponding exosomes revealed the same heterozygous mutation pattern in RET, HIF2A, VHL, and SDHB mutations. B Sanger sequencing of serum exosome-derived DNA revealed RET, VHL, HIF2A, and SDHB mutations in tissues from PCC and PCL patients

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Molecular Cancer

ISSN: 1476-4598