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Fig. 2 | Molecular Cancer

Fig. 2

From: Brain-derived neurotrophic factor, a new soluble biomarker for malignant pleural mesothelioma involved in angiogenesis

Fig. 2

Diagnostic and prognostic value of BDNF in pleural effusions from patients. Pleural fluid BDNF values a in patients with MPM, other neoplasia or BPE or b in patients with MPM or other effusions (neoplasia and BPE). Red bars correspond to median. ***p < 0.001. MPM. malignant pleural mesothelioma; BPE. benign pleural effusion. c ROC curve for BDNF to distinguish between patients with MPM and patients with other malignant and/or benign effusions. d Overall Survival of MPM patients. Patients were separated in “high expression” and “low expression” groups based on the BDNF expression median in MPM PE and differences in survival between two groups are assessed by log-rank tests

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