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Fig. 1 | Molecular Cancer

Fig. 1

From: Expression signatures of exosomal long non-coding RNAs in urine serve as novel non-invasive biomarkers for diagnosis and recurrence prediction of bladder cancer

Fig. 1

Characterization of UEs. a UEs were analyzed under TEM which exhibited a cup-shaped membrane morphology with a diameter of 60–150 nm. Typical exosomes were highlighted using white arrows. Left figure: scale bar = 200 nm; Right figure scale bar = 100 nm. b UEs-enriched protein markers including CD9 (24KD) and TSG101 (50KD) were analyzed by Western blotting in exosomes (E) and exosome-depleted supernatant (EDS). Three urine samples were used. c The sizes of urine exosomes were characterized via the NTA characterization system and the majority of vesicle particles were mainly between 60 and 150 nm in diameter. d Flow cytometry analysis was performed to detect the positive rate of CD63 and CD81 specific antibodies on the surface of exosomes

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Molecular Cancer

ISSN: 1476-4598