The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Table 2 Univariate and multivariate analysis of clinic pathologic factors for overall survival in 130 CRC patients

Risk factors	Univariate analysis		Multivariate analysis
Risk factors	HR (95% CI)	P value ^a	HR (95% CI)	P value ^a
SNHG1 expression (Low vs. High expression)	2.96 (1.64–5.37)	< 0.001	2.82 (1.53–5.18)	0.001
TNM stage (I/II vs. III/IV)	2.80 (1.59–4.93)	< 0.001	1.12 (0.52–2.42)	0.773
Tumor invasion depth (T1/T2 vs. T3/T4)	1.39 (0.76–2.53)	0.281
Lymph node metastasis (N0 vs. N1 or above)	1.22 (0.64–2.31)	0.549
Distant metastasis (M0 vs. M1)	4.69 (2.49–8.83)	< 0.001	4.15 (1.76–9.77)	0.001
Age (≤60 vs. > 60)	0.99 (0.56–1.72)	0.934
Gender (Male vs. Female)	0.84 (0.48–1.49)	0.551

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