Skip to main content

Advertisement

Table 2 Univariate and multivariate analysis of clinic pathologic factors for overall survival in 130 CRC patients

From: The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Risk factors Univariate analysis Multivariate analysis
HR (95% CI) P value a HR (95% CI) P value a
SNHG1 expression (Low vs. High expression) 2.96 (1.64–5.37) < 0.001 2.82 (1.53–5.18) 0.001
TNM stage (I/II vs. III/IV) 2.80 (1.59–4.93) < 0.001 1.12 (0.52–2.42) 0.773
Tumor invasion depth (T1/T2 vs. T3/T4) 1.39 (0.76–2.53) 0.281   
Lymph node metastasis (N0 vs. N1 or above) 1.22 (0.64–2.31) 0.549   
Distant metastasis (M0 vs. M1) 4.69 (2.49–8.83) < 0.001 4.15 (1.76–9.77) 0.001
Age (≤60 vs. >  60) 0.99 (0.56–1.72) 0.934   
Gender (Male vs. Female) 0.84 (0.48–1.49) 0.551   
  1. HR hazard ratio; CI confidential interval; vs. versus
  2. aStatistical significant results (in bold)