From: Effect of exosomal miRNA on cancer biology and clinical applications
Immuno | Exosomal miRNA | Involved molecule | Involved other molecules | Function | Ref. |
---|---|---|---|---|---|
DCs | miR-203 | TLR4 | TNF-α, IL-12 pathway | DCs dysfunction in pancreatic cancer | [42] |
miR-212-3p | RFXAP | / | Immune tolerance of DCs in pancreatic cancer | [36] | |
Lymphocytes | miR-183 | DAP12 | TGFβ | NK | [94] |
miR-210 | NKG2D | TGFβ1 | NK | [45] | |
miR-23 | CD107a | / | NK | [95] | |
miR-20a | MICA/MICB | NKG2D | NK | [96] | |
miR-10b | MICB | / | NK | [97] | |
miR-92a | / | FasL, INF-Ï’ | NKT | [98] | |
miR-214 | PTEN | IL-10 | T cell | [99] |