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Fig. 4 | Molecular Cancer

Fig. 4

From: Circular RNA YAP1 inhibits the proliferation and invasion of gastric cancer cells by regulating the miR-367-5p/p27 Kip1 axis

Fig. 4

Knockdown circYAP1 promotes proliferation, colony formation and migration. a, Schematic representation of the target sequences of the siRNAs specific to the back-splicing junction of circYAP1. b-c, Cell proliferation activity and d, DNA synthesis in HGC-27 cells transfected with si-circYAP1 or si-circYAP1 + miR-367-5p inhibitor. e, Clone formation assays of HGC-27 cells transfected with si-circYAP1 or si-circYAP1 + miR-367-5p inhibitor. f, Cell invasion potential of HGC-27 cells transfected with si-circYAP1 or si-circYAP1 + miR-367-5p inhibitor according to Transwell assays. *P < 0.05; **P < 0.01

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