Fig. 3From: High expression of Tob1 indicates poor survival outcome and promotes tumour progression via a Wnt positive feedback loop in colon cancerTob1 stimulates proliferation and Wnt signalling in vivo. a Experimental procedures for the AOM/DSS model. b-d Colon tumour incidence, number and volume in mice. *, P < 0.05. e-f Representative IHC micrographs of PHH3, Ki-67 and cyclin D1 in colon tumours of different mouse models. g ISH analysis of Tob1 expression in the colon tissues of ApcMin/+ miceBack to article page