Fig. 2

The expression and clinical significance of circFNDC3B in BC. a The expression of circFNDC3B in BC cell lines was detected by qRT-PCR. b and c qRT-PCR analysis of circFNDC3B in 56 paired BC and adjacent noncancerous tissues. d-h The expression levels of circFNDC3B in BC patients with different pathological T stages, grades, lymph node status, and vascular invasion status. LN represents lymph node. i Kaplan-Meier survival curve indicated that patients with low circFNDC3B expression had low survival rates. a, **P < 0.01 (Student’s t-test); b, **P < 0.01 (Wilcoxon rank-sum test); d-h, **P < 0.01, ***P < 0.001 (Mann-Whitney U-test)