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Fig. 7 | Molecular Cancer

Fig. 7

From: Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis

Fig. 7

Overexpression of circFNDC3B reverses the oncogenic roles of miR-1178-3p in BC cells. a-c The colony formation (a), migration (b), and invasion (c) abilities enhanced by miR-1178-3p were reversed after cotransfection with circFNDC3B using colony formation assay, transwell migration assay and Matrigel invasion assay. Scale bar, 100 μm. d and e The upregulation of G3BP2, p-SRC and p-FAK in T24 and UM-UC-3 cells transfected with miR-1178-3p mimics was reversed by overexpression of circFNDC3B as detected by western blot. Data are presented as the means±SEM of three experiments. *P < 0.05, **P < 0.01 (Student’s t-test)

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