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Fig. 4 | Molecular Cancer

Fig. 4

From: CircSLC3A2 functions as an oncogenic factor in hepatocellular carcinoma by sponging miR-490-3p and regulating PPM1F expression

Fig. 4

Identification of PPM1F as a direct target of miR-490-3p in HCC cells. a qRT-PCR analysis of the expression levels of miR-490-3p in different HCC cell lines. b, c qRT-PCR and Western blot analysis of the expression levels of miR-490-3p and PPM1F after transfection with miR-490-3p mimic in HepG2 cell line or its inhibitor in LO2 cell line. d The binding sites of miR-490-3p with WT or Mut PPM1F 3′UTR. e, f Luciferase activity of WT or Mut PPM1F 3′UTR after transfection with miR-490-3p mimic or inhibitor in HepG2 or LO2 cell line. Data are the means ± SEM of three experiments. * P < 0.05; ** P < 0.01

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