Skip to main content
Fig. 1 | Molecular Cancer

Fig. 1

From: TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling

Fig. 1

TRIB2 expression is elevated in CRC patients. a Analysis of TRIB2 expression in CRC and normal tissues from two colorectal cancer cohorts. The gene expression data (GSE41258, GSE20916) was downloaded from GEO database (** p < 0.01, *** p < 0.001, t-test). b Analysis of TRIB2 expression in CRC tissues from patients with or without recurrence. The gene expression data (GSE21510) was downloaded from GEO database (* p < 0.05, t-test). c Elevated TRIB2 expression was correlated with tumor grade. The gene expression data (GSE25071) was downloaded from GEO database (** p < 0.01, t-test). d Kaplan–Meier plot of overall Survival: patients with CRC (TCGA database and GSE17536 from GEO database) were stratified by TRIB2 expression level. e Cox regression analysis to evaluate the significance of the association between TRIB2 expression and CRC patients prognosis in the presence of other clinical variables. f mRNA expression of TRIB2 in 15 pairs of human primary CRC tissues (normal and Tumor). g Representative examples of TRIB2 staining in CRC and adjacent normal tissues. h and i Quantification of TRIB2 expression in normal and CRC samples

Back to article page