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Fig. 2 | Molecular Cancer

Fig. 2

From: Comparative proteogenomic analysis of right-sided colon cancer, left-sided colon cancer and rectal cancer reveals distinct mutational profiles

Fig. 2

a shows the frequency of APC hotspot the R1450 residue in (i) right-sided colon cancers, (ii) left-sided colon cancers and (iii) rectal cancers in TCGA (left) and MSKCC (right) datasets. Y-axis represent total number of mutations at each residue. b shows the mutual exclusivity of APC R1450* (APC_1450) compared to other genes of β-Catenin destruction complex in RCC. “APC_MCR” represents other APC mutations within the MCR region that are not at the 1450 residue. The bar plot above the oncoplot represents total mutations in each sample

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Molecular Cancer

ISSN: 1476-4598