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Fig. 2 | Molecular Cancer

Fig. 2

From: RETRACTED ARTICLE: Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer

Fig. 2

TINCR is upregulated in trastuzumab-res`istant cells. a The heat map showed the significantly increased and decreased lncRNAs in SKBR-3TR and BT474TR cells when compared to respective parental cells analyzed by Agilent human lncRNA microarray. Three repeated samples were used for each cell type. b The expression level of TINCR in cells was measured by using qPCR. **P < 0.01, ***P < 0.001 compared to parental cell group. c TINCR expression was detected in breast cancer patients who showed response or non-response to trastuzumab treatment. **P < 0.01

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Molecular Cancer

ISSN: 1476-4598