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Table 1 The expression level of circNRIP1 is significantly correlated with the GC tumour size and lymphatic invasion, and the expression level of miR-149-5p is negatively correlated with the GC tumour size

From: Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway

Parameters

Group

circNRIP1 expression

miR-149-5p expression

Cases

Low

High

P-value

Cases

Low

High

P-value

Gender

female

24

11

13

0.6256

15

7

8

0.6212

male

56

29

27

35

19

16

Age at surgery

≥55

64

34

30

0.2636

33

17

16

0.7653

< 55

16

6

10

17

8

9

T grade

T1 + T2

40

22

18

0.3711

24

11

13

0.5713

T3 + T4

40

18

22

26

14

12

Lymphatic invasion

Negative (N0)

14

11

3

0.0186*

15

5

10

0.1228

Positive (N1-N3)

66

29

37

35

20

15

Tumor site

Cardiac

30

21

9

0.1689

18

7

11

0.2386

Non-cardiac

50

19

31

32

18

14

Stage

I-II

43

24

19

0.2622

23

11

12

0.7766

III-IV

37

16

21

27

14

13

Size(cm)

< 3

37

23

14

0.0436*

24

8

16

0.0235*

≥3

43

17

26

26

17

9

Histology grade

Well-moderately

28

13

15

0.6392

16

7

9

0.5443

Poorly-signet

52

27

25

34

18

16

  1. All data are presented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001
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Molecular Cancer

ISSN: 1476-4598