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Fig. 2 | Molecular Cancer

Fig. 2

From: Novel long noncoding RNA OTUD6B-AS1 indicates poor prognosis and inhibits clear cell renal cell carcinoma proliferation via the Wnt/β-catenin signaling pathway

Fig. 2

LncRNA OTUD6B-AS1 expression was downregulated in ccRCC tissue and associated with clinicopathological features of patients with ccRCC. (a, b) The relative expression of OTUD6B-AS1 in ccRCC tissue (n = 75) compared with corresponding adjacent normal tissue (n = 75) is shown. OTUD6B-AS1 expression was examined by qRT-PCR and normalized to GAPDH expression (shown as the -ΔCT method). c The expression levels of OTUD6B-AS1 were determined by qRT-PCR in different clinical stage ccRCC tissue samples. d The ROC curve was constructed using SPSS. The area under the curve was 0.792. The sensitivity and specificity were 0.773 and 0.813, respectively. e The survival time of the patients with high OTUD6B-AS1 expression (n = 26) was longer than that of the patients with low OTUD6B-AS1 expression (n = 26). The data represent the mean ± SD of 3 replicates. * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001

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Molecular Cancer

ISSN: 1476-4598