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Fig. 4 | Molecular Cancer

Fig. 4

From: Novel long noncoding RNA OTUD6B-AS1 indicates poor prognosis and inhibits clear cell renal cell carcinoma proliferation via the Wnt/β-catenin signaling pathway

Fig. 4

OTUD6B-AS1 overexpression inhibited the migration and invasion of ccRCC cells in vitro. (a, b) Transwell assays with Matrigel for cell invasion with the ACHN and OS-RC-2 cell lines transfected with plvx-OTUD6B-AS1 or the empty vector; c western blot analysis of MMP9 expression in cells transfected with plvx-OTUD6B-AS1 or the empty vector. β-Actin internal control. d, e Transwell assays without Matrigel for cell migration with the ACHN and OS-RC-2 cell lines transfected with plvx-OTUD6B-AS1 or the empty vector. The data represent the mean ± SD of 3 replicates. *Indicates a significant difference between the empty vector group and the plvx-OTUD6B-AS1 group. * P < 0.05, **P < 0.01

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Molecular Cancer

ISSN: 1476-4598