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Fig. 6 | Molecular Cancer

Fig. 6

From: Novel long noncoding RNA OTUD6B-AS1 indicates poor prognosis and inhibits clear cell renal cell carcinoma proliferation via the Wnt/β-catenin signaling pathway

Fig. 6

Overexpression of OTUD6B-AS1 decreased the activity of the Wnt/β-catenin pathway and suppressed the expression of EMT-related proteins. a Kyoto Encyclopedia of Genes and Genomes analysis revealed that the Wnt signaling pathway was significantly altered in ccRCC. b The effect of OTUD6B-AS1 on the Wnt/β-catenin signaling pathway was analyzed by western blotting with the indicated antibodies and samples from the ACHN and OS-RC-2 cells transfected with plvx-OTUD6B-AS1 or the empty vector. c The effect of OTUD6B-AS1 on EMT-related proteins was analyzed by western blotting with the indicated antibodies and samples from the ACHN and OS-RC-2 cells transfected with plvx-OTUD6B-AS1 or the empty vector

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Molecular Cancer

ISSN: 1476-4598