Skip to main content
Fig. 7 | Molecular Cancer

Fig. 7

From: Novel long noncoding RNA OTUD6B-AS1 indicates poor prognosis and inhibits clear cell renal cell carcinoma proliferation via the Wnt/β-catenin signaling pathway

Fig. 7

OTUD6B-AS1 inhibited the tumorigenesis of ccRCC cells in vivo. a The empty vector or plvx-OTUD6B-AS1 was transfected into ACHN cells, which were then injected into nude mice (n = 6). The tumors formed in the plvx-OTUD6B-AS1 group were dramatically smaller than those formed in the control group. b Tumor volumes were calculated after injection every four days. Points indicate means (n = 6); bars indicate SDs. c Tumor weights are represented as the mean tumor weight ± SD. d qRT-PCR was performed to detect the average expression of OTUD6B-AS1 in the xenograft tumors (n = 6). e The tumor sections were subjected to H&E staining and IHC staining using antibodies against ki-67. * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001

Back to article page