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Table 3 The application of autophagy inhibitors in tumor immunotherapy

From: The relationship between autophagy and the immune system and its applications for tumor immunotherapy

Autophagy Inhibitors

Tumor Types

Autophagy-Modulating Mechanism

Research Types

Chloroquine

Renal cell carcinoma

Improve HDIL-2-mediated anti-tumor immunity by enhancing DCs, T-cells and NK cells [177]

Preclinical

3-methyladenine (3-MA)

Oral squamous cell Carcinomas

Significantly enhance IL-24-induced apoptosis [178]

Preclinical