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Fig. 6 | Molecular Cancer

Fig. 6

From: Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer

Fig. 6

MiR-143 mimics reverse the oncogenic function of PVT1 in vitro. (a-b) CCK-8 assay showed that the introduction of miR-143 mimics attenuated the proliferation-promoting effect of PVT1 in GBC cells. (c-d) The introduction of miR-143 mimics attenuated the colony formation-promoting effect of PVT1 in GBC cells. (e-h) The abilities of cell invasion and migration induced by PVT1 were significantly attenuated after the introduction of miR-143 mimics in GBC-SD and NOZ cells, as measured by transwell assay (magnification, × 100). Scale bar, 100 μm and wound healing assays. *P < 0.05, **P < 0.01, ***P < 0.001. Error bars indicate mean ± SD

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