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Fig. 7 | Molecular Cancer

Fig. 7

From: Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer

Fig. 7

The PVT1/miR-143/HK2 axis regulates glucose metabolism in GBC cells. (a-b) The effects of si-PVT1, miR-143 inhibitor and si-PVT1 + miR-143 inhibitor on glucose consumption and cellular lactate production levels in GBC-SD cells. (c-d) The effects of miR-143 mimics, pcDNA-PVT1, and miR-143 mimics+pcDNA-PVT1 on glucose consumption and cellular lactate production levels in GBC-SD cells. (e-f) ECAR was detected by the Glycolysis Stress Test in GBC-SD cells after transfection with si-PVT1 or si-NC. (g-h) OCR was measured by the Cell Mito Stress Test in GBC-SD cells after transfection with si-PVT1 or si-NC. *P < 0.05, **P < 0.01, ***P < 0.001. Error bars indicate mean ± SD

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