Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer

Table 1 The relationship between PVT1 expression status and clinic-pathologic features of gallbladder cancer

	Clinicopathological features	No. of cases(n)	PVT1 expression		P	HK2 expression		P
	Clinicopathological features	No. of cases(n)	High(n = 33)	Low(n = 33)	P	High(n = 30)	Low(n = 36)	P
Age(years)	<median	33	17	16	0.806	14	19	0.825
Age(years)	>median	33	16	17		16	17
Gender	Male	19	10	9	0.786	7	12	0.341
Gender	Female	47	23	24		23	24
Tumor size	< 5 cm	35	17	18	0.805	15	20	0.874
Tumor size	> 5 cm	31	16	15		15	16
TNM stage	Stage I and II	31	11	20	0.026^*	9	22	0.042^*
TNM stage	Stage III and IV	35	22	13		21	14
Distant metastasis	Absent	37	16	21	0.215	12	25	0.033^*
Distant metastasis	Present	29	17	12		18	11
Differentiation grade	Stage I and II	28	11	17	0.135	8	20	0.004^*
Differentiation grade	Stage III and IV	38	22	16		22	16

Abbreviations: TNM = tumor-node-metastasis; PVT1 = plasmacytoma variant translocation 1; HK2 = Hexokinase 2; ^*P < .05

ISSN: 1476-4598