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Fig. 1 | Molecular Cancer

Fig. 1

From: Exosomal FMR1-AS1 facilitates maintaining cancer stem-like cell dynamic equilibrium via TLR7/NFκB/c-Myc signaling in female esophageal carcinoma

Fig. 1

Female specific X-associated lncRNA screening and FMR1-AS1 expression patterns in female ESCC samples and cells. a The venn diagram in (A) depicts the number of gene probes that are differentially expressed in the female ESCC group versus male. b The distribution of those female differentially expressed genes on each chromosome after annotation. c The heat map shows all 142 differentially expressed genes (p < 0.001) specific in female ESCC microarray samples, red = upregulated genes; green = downregulated genes. d LncRNAs that differentially expressed in female ESCC microarray samples. e FMR1-AS1 expression in female ESCC and matched non-tumor tissues from Suzhou (n = 206) and Guangzhou (n = 188) (***p < 0.001). f Kaplan-Meier plots for the disease-free survival rate of female ESCC patients in groups of FMR1-AS1 high or low expression levels in the Suzhou cohort (n = 206, discovery set), Guangzhou cohort (n = 188, validation set), and pooled populations (n = 394, pooled analysis). g Northern-blot of FMR1-AS1 in two pairs of ESCC tissue samples

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