Fig. 2
From: Natural killer group 2D receptor and its ligands in cancer immune escape
NKG2D receptor and its ligand. MICA\B has α1–3 domains, a transmembrane structure, and a cytoplasmic tail. ULBP1–6 have only the α1 and α2 domains; among these, ULBP1, − 2, − 3, and − 6 have a GPI-anchoring structure, and ULBP4 and − 5 have a transmembrane structure and a cytoplasmic tail. NKG2D is a homodimer of a type II transmembrane glycoprotein that binds noncovalently to DAP10 in the transmembrane domain