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Fig. 4 | Molecular Cancer

Fig. 4

From: A novel lncRNA MCM3AP-AS1 promotes the growth of hepatocellular carcinoma by targeting miR-194-5p/FOXA1 axis

Fig. 4

MCM3AP-AS1 knockdown suppresses HCC growth in vivo. a Hep3B cells that were stably transfected with MCM3AP-AS1 shRNA (n = 6) or control shRNA (n = 6) were subcutaneously injected into nude mice. Tumor growth curves indicated that MCM3AP-AS1 knockdown led HCC growth restriction in mice. *P < 0.05 by ANOVA. Scale bar: 1 cm. b The subcutaneous tumors were harvested and weighted at the 21st day after implantation. *P < 0.05 by Student’s t-test. c Xenograft tissues were subjected to qRT-PCR for MCM3AP-AS1 expression. *P < 0.05 by Student’s t-test. d Immunostaining of Ki-67 in xenograft tissues arising from MCM3AP-AS1 knockdown group and control group. Scale bar: 50 μm. *P < 0.05 by Student’s t-test

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Molecular Cancer

ISSN: 1476-4598