TY - JOUR AU - Plava, Jana AU - Cihova, Marina AU - Burikova, Monika AU - Matuskova, Miroslava AU - Kucerova, Lucia AU - Miklikova, Svetlana PY - 2019 DA - 2019/03/30 TI - Recent advances in understanding tumor stroma-mediated chemoresistance in breast cancer JO - Molecular Cancer SP - 67 VL - 18 IS - 1 AB - Although solid tumors comprise malignant cells, they also contain many different non-malignant cell types in their micro-environment. The cellular components of the tumor stroma consist of immune and endothelial cells combined with a heterogeneous population of stromal cells which include cancer-associated fibroblasts. The bi-directional interactions between tumor and stromal cells therefore substantially affect tumor cell biology. SN - 1476-4598 UR - https://doi.org/10.1186/s12943-019-0960-z DO - 10.1186/s12943-019-0960-z ID - Plava2019 ER -