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Fig. 2 | Molecular Cancer

Fig. 2

From: The roles of extracellular vesicles in gastric cancer development, microenvironment, anti-cancer drug resistance, and therapy

Fig. 2

Functions of cancer derived EVs in GC progression and metastasis. The first general mechanism is that GC cells-derived EVs promote tumor cells growth and metastasis through overexpression of multiple proteins, miRNAs and LncRNAs. The second general mechanism is that metastasis, including lymphtic, peritoneal, and liver-specific metastasis, which can be induced by tumor-derived EVs via different pathways in GC. Abbreviations: EGFR, epidermal growth factor receptor

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