Fig. 1From: Therapy resistance mediated by exosomesExosomal cargo that mediates therapy resistance. Exosomes cause therapy resistance in the recipient cell by transporting DNA, RNA (micro RNA, short interfering RNA), lipids and proteins. They cause decreased apoptosis and anti tumor immunosurveillance and increased DNA repair and stemness in recipient cells. Furthermore they transport multidrug resistance (MDR) transporter to recipient cells or integrate them in reverse orientation in their membrane to decrease intra- and intercellular drug concentrationBack to article page