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Fig. 3 | Molecular Cancer

Fig. 3

From: MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells

Fig. 3

MiR155 induced interaction of B-lymphoma cells with CD8+T cells and Fas-mediated CD8+T cell apoptosis. a and b: Percentage of CD8+T cells (a) was increased and CD8+T cell apoptosis (b) was inhibited when co-cultured with Farage cells transfected with miR155 inhibitor. c and d: Percentage of CD8+T cells (c) was decreased and CD8+T cell apoptosis (d) was enhanced when co-cultured with DB cells transfected with miR155 mimics. e and f: Fas expression of CD8+T cells was downregulated when co-cultured with Farage cells transfected with miR155 inhibitor (e), which was upregulated when co-cultured with DB cells transfected with miR155 mimics (f)

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