Table 1 Univariate and multivariate analysis of factors associated
Variables | Low miR-128 (n = 61) | High miR-128 (n = 61) | ||
|---|---|---|---|---|
Harzard ratio (95% CI) | P value | Harzard ratio (95% CI) | P value | |
Univariate analysis | ||||
 Oxaliplatin vs control | 0.734(0.405–1.330) | 0.308 | 0.295(0.137–0.637) | 0.002* |
 Gender (male vs female) | 1.310(0.732–2.345) | 0.363 | 1.190(0.559–2.534) | 0.652 |
 Age (> 60 vs ≤60 years) | 1.197(0.670–2.141) | 0.544 | 1.215(0.571–2.586) | 0.613 |
 Tumor size (≤4 vs > 4 cm) | 1.411(0.781–2.550) | 0.253 | 0.720(0.315–1.645) | 0.436 |
 Tumor location (Rectum vs colon) | 0.618(0.340–1.121) | 0.113 | 1.293(0.600–2.789) | 0.512 |
 Tumor differentiation (Well/Moderate vs Poor) | 0.890(0.492–1.611) | 0.701 | 0.802(0.372–1.729) | 0.573 |
 TNM stage (II vs III/IV) | 0.559(0.280–1.118) | 0.100 | 1.259(0.435–3.646) | 0.671 |
 Distant metastasis (NO vs YES) | 1.117(0.587–2.124) | 0.736 | 2.203(0.883–5.498) | 0.090 |
Multivariate analysis | ||||
 Oxaliplain vs control | 0.311(0.140–0.688) | 0.004* | ||
 Gender (male vs female) | 0.947(0.391–2.293) | 0.905 | ||
 Age (> 60 vs ≤60 years) | 0.898(0.385–2.093) | 0.803 | ||
 Tumor size (≤4 vs > 4 cm) | 0.805(0.285–2.276) | 0.683 | ||
 Tumor location (Rectum vs colon) | 0.913(0.315–2.650) | 0.868 | ||
 Tumor differentiation (Well vs Moderate/Poor) | 1.210(0.412–3.551) | 0.729 | ||
 TNM stage (II vs III/IV) | 1.046(0.306–3.576) | 0.943 | ||
 Distant metastasis (NO vs YES) | 2.014(0.484–8.380) | 0.336 | ||