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Fig. 1 | Molecular Cancer

Fig. 1

From: Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma

Fig. 1

Abnormal expression of HOTAIR is associated with exosome secretion. a Heatmap showing the relative expression values for 31 exosome secretion-related genes in a series of 374 cases of liver cancer generated from TCGA and categorized into subgroups according to their median HOTAIR expression. The list on the right shows 31 genes involved in exosome secretion. b Enrichment plot showing enrichment of exosome secretion-related genes in the HOTAIR high expression group. c-e The mRNA expression of RAB35, SNAP23, and VAMP3 were analyzed in HCC tissues compared with normal tissues. f-h The mRNA expression of RAB35, SNAP23, and VAMP3 were analyzed in HOTAIR relative high group compared with HOTAIR relative low group.t-test *P-value < 0.05

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