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Fig. 3 | Molecular Cancer

Fig. 3

From: Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma

Fig. 3

HOTAIR enhances the transport of MVBs towards the plasma membrane. a Confocal microscopy analysis of CD63 (red) in HepG2 cells transfected with pcDNA3.1-HOTAIR. Nuclei were stained with DAPI. b Confocal co-localization analysis of CD63 (red) and SNAP23 (green) in HepG2 cells transfected with pcDNA3.1-HOTAIR. The rectangular box indicates the small punctate structures where CD63 and SNAP-23 were co-localized. c Electron microscopy images showing MVBs in HepG2 cells transfected with pcDNA3.1 or pcDNA3.1-HOTAIR. Red arrows indicated MVBs

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