Fig. 2
From: Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
Tumor-derived exosomes promotes angiogenesis. Tumor derived exosomes promotes vascular formation. VEGF, Platelet-derived growth factor (PDGF), basic fibroblast growth factor (bFGF), transforming growth factor β (TGF-β), tumor necrosis factor α (TNF-α), syndecan-4, Glypican-1, interleukin-8 (IL-8), Malat1, Dil4 and some microRNAs are some of the angiogenic stimulatory factors which can be carried by tumor exosomes