Fig. 3From: Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistanceTumor derived exosomes promote Epithelial Mesenchymal Transition (EMT) and Invasion. EMT initiators include TGF-β, HIF1α, β-catenin, IL-6, β-catenin or Vimentin, Casein Kinase and several miRNAs are among the essential EMT promoting factors that are carried by the tumor derived exosomes. Zeb family members are the main players in EMT transitionBack to article page