Fig. 1
From: Genome-wide identification of cancer-specific alternative splicing in circRNA
Identification and characterization of circ-AS patterns in cancer and adjacent normal tissues. a. The ratio of the four types of circ-AS (SE, RI, A5SS, A3SS) in ccRCC and adjacent normal tissues. b. The ratio of the four types of circ-AS in bladder cancer and adjacent normal tissues. c. Validation of one A5SS event happened in circ-UBAP2L. Top: The light blue box represents the constitutive exon of circRNA and the light green box represents the alternative exon of circRNA. The arrows represent the position of PCR primers. Bottom: RT-PCR of two circRNA isoforms generated by circ-AS. d. Validation of one SE event happened in circ-RAB6A. e. The average length of the four types of circ-AS in ccRCC and adjacent normal tissues. f. The average length of the four types of circ-AS in bladder cancer and adjacent normal tissues. The error bar represents the Standard Error. g. The distribution of circ-AS event in lncRNA and mRNA between ccRCC and adjacent normal tissues. h. The distribution of circ-AS in lncRNA and mRNA between bladder cancer and adjacent normal tissues