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Fig. 5 | Molecular Cancer

Fig. 5

From: A positive feed-forward loop between LncRNA-URRCC and EGFL7/P-AKT/FOXO3 signaling promotes proliferation and metastasis of clear cell renal cell carcinoma

Fig. 5

URRCC is associated with EGFL7/P-AKT/FOXO3 signaling pathway. a and b: WB analysis of T-AKT, P-AKT, and FOXO3 in URRCC-overexpressing or URRCC-inhibited A498 and OSRC-2 cells compared with sh-control or mock group, β-actin was used as a loading control. c: CCK8 assays of A498 cells transfected with mock/oe-URRCC and si-NC/si-EGFL7. d: Representative images and the numbers of invasive cells per high-power field reduced after the transfection with mock/oe-URRCC and si-NC/si-EGFL7 in A498 cells. e: WB analysis for EGFL7, T-AKT, P-AKT, and FOXO3 protein levels of A498 cells transfected with mock/oe-URRCC and si-NC/si-EGFL7. β-actin was used as a loading control

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Molecular Cancer

ISSN: 1476-4598