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Fig. 1 | Molecular Cancer

Fig. 1

From: A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling

Fig. 1

CircRNA expression profile in CC and characterization of circPPP1R12A. a Heatmap of the differentially expressed circRNAs in 10 pairs of human CC tissues and matched non-tumor tissues. b Classification of dysregulated circRNAs. c CircPPP1R12A was back-spliced by exons 24 and 25 of PPP1R12A gene located at 12q21.2. d The expression level of circPPP1R12A in CC and matched non-tumor tissue samples from 20 patients was analyzed by real-time PCR. e The expression level of circPPP1R12A in a series of cultured CC cell lines (HT-29, HCT-116, SW480, SW620, LoVo, SW48, DLD-1, Caco2 and HCT-15) was analyzed by real-time PCR. ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598