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Table 2 Univariate and multivariate survival analysis of CC patients from SEER database

From: A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling

Variable Univariate analysis Multivariate analysis
HR (95% CI) P HR (95% CI) P
Sex (Male vs. Female) 0.935 (0.543–1.611) 0.809   
Age (>  55 vs. 16–55 years) 1.620 (0.584–4.495) 0.354   
Tumor size (cm) (>  5 vs. 0–5) 1.007 (0.562–1.802) 0.982   
Pathological stage (III vs. I + II) 2.815 (1.520–5.215) 0.001 2.865 (1.521–5.394) 0.001
Pathological type (Massive vs. Nodular) 1.565 (0.907–2.701) 0.108   
circPPP1R12A ISH Score (3–4 vs. 0–2) 2.788 (1.484–5.237) 0.001 2.927 (1.574–5.443) 0.001
  1. Abbreviation: ISH, In Situ Hybridization
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