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Fig. 5 | Molecular Cancer

Fig. 5

From: CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling

Fig. 5

The effects of circDLST on in vivo tumor growth and liver metastasis. a Comparison of the tumor size of xenograft tumors induced by sh-circDLST and sh-NC transfected MKN-45 cells. b A growth curve analysis of the tumor growth in sh-circDLST and sh-NC transfected MKN-45 groups. c Comparison of the body weight in sh-circDLST and sh-NC transfected MKN-45 groups. d Comparison of the liver metastatic tumors from sh-circDLST and sh-NC transfected gastric tumor tissues. e HE staining of the metastatic tumor cells in liver tissues in sh-circDLST and sh-NC groups. f, g Comparison of the liver tumor size and body weight in sh-circDLST and sh-NC groups. h Comparison of the tumor size of xenograft tumors induced by circDLST or vector transfected BGC-823 cells. i A growth curve analysis of the tumor growth in circDLST or vector transfected BGC-823 groups. Bar scale: 250 μm. Data are the means ± SEM of three experiments. *P < 0.05

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