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Fig. 7 | Molecular Cancer

Fig. 7

From: CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling

Fig. 7

MiR-502-5p reversed the tumor promoting effects of circDLST in GC cells. a qRT-PCR analysis of the transfection efficiency of miR-502-5p inhibitor in MKN-28 cells or miR-502-5p mimic in BGC-823 cells. b, c MTT analysis of the cell viability after the co-transfection of miR-502-5p inhibitor and sh-circDLST in MKN-28 cells or miR-502-5p mimic and circDLST in BGC-823 cells. d, e Colony formation analysis of the colony number after the co-transfection of miR-502-5p inhibitor and sh-circDLST in MKN-28 cells or miR-502-5p mimic and circDLST in BGC-823 cells. f, g Transwell analysis of the cell invasive potential after the co-transfection of miR-502-5p inhibitor and sh-circDLST in MKN-28 cells or miR-502-5p mimic and circDLST in BGC-823 cells. Bar scale: 125 μm. Data are the means ± SEM of three experiments. *P < 0.05; **P < 0.01

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